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Intussusception
Intussusception
Intussusception is a rare but serious disorder in which part of the intestine; either the small intestine or colon slides into another part of the intestine. This "telescoping" often blocks the intestine, preventing food or fluid from passing through. Intussusception also cuts off the blood supply to the part of the intestine that's affected. Intussusception is the most common cause of intestinal obstruction among infants. In contrast, most cases in children have no known cause.Signs & Symptoms
Intussusception requires emergency medical care. If your child develops the following signs or symptoms, seek medical help right away:
- Severe abdominal pain that comes and goes (intermittent pain)
- Stool mixed with blood and mucus
- A lump in the abdomen
- Swollen (distended) abdomen
- Vomiting
- Diarrhea
- Fever
- Dehydration
- Lethargy
For most cases of intussusception in children, the cause is unknown. Viral infection or a growth in the intestine, such as a polyp, lymph node or tumor, may trigger it. In the past, some cases of intussusception seemed to be associated with a version of the rotavirus vaccine. Rotavirus is a childhood illness that causes severe diarrhea, vomiting, fever and dehydration. That vaccine was removed from the market in 1999. There's no evidence that the rotavirus vaccine currently available (RotaTeq) causes intussusception. On February 13, 2007 the U.S. government issued a warning that RotaTeq can cause intussusception in infants.
Diagnosis
Your infant's physician may recommend several test, including the following:
- X-ray or other abdominal imaging. Taking images of your child's abdomen with X-ray, ultrasound or computerized tomography (CT) scans may reveal intestinal obstruction caused by intussusception. Abdominal imaging also can show if the intestine has been torn (perforated).
- Barium or air enema. A barium enema is basically a colon X-ray. During the exam, the doctor will insert liquid barium or in some cases air into your child's colon through the rectum. This makes the pictures on the X-ray clearer. Sometimes a barium or air enema will correct intussusception, and no further treatment is needed. A barium enema can't be used if the intestine is torn.
IntussusceptionRSS Feed
CDC Releases Safety Data on Rotavirus Vaccine; Reported Intussusception Cases Fall Within Expected Range
Mar 16, 2007 | www.infectioncontroltoday.com
The Centers for Disease Control and Prevention (CDC) has released new safety data on a recently licensed rotavirus vaccine given to infants that indicate the vaccine does not pose an elevated risk for intussusception, the most common cause of bowel obstruction in infants. The vaccine, sold by Merck and Company under the brand name RotaTeq, was licensed by the Food and Drug Administration (FDA) in February 2006. The Advisory Committee on Immunization Practices (ACIP) recommends RotaTeq for...
State to continue using vaccine against rotavirus
Feb 15, 2007 | The Birmingham News
Alabama's Department of Public Health has dispensed more than 50,000 doses of an early childhood vaccine that is the subject of an FDA public health notification about intestinal problems in infants, an official said Wednesday. Winkler Sims, head of the state Department of Public Health's immunization division, said the state began distributing the RotaTeq vaccine in July to more than 500 sites that participate in the Children's Vaccine Program. Private providers also have been using the...
Intestinal Woes, Vaccine May Be Linked
Feb 14, 2007 | AP
The Food and Drug Administration warned yesterday of potentially life-threatening twisting of the intestines in infants vaccinated against a virus that is the leading cause of early-childhood diarrhea. The condition, called intussusception, is the same that led to the withdrawal of the first rotavirus vaccine eight years ago. The FDA said it was unknown whether the recently approved vaccine, called RotaTeq, caused the 28 new cases of the condition, which also can occur spontaneously. Indeed,...
FDA notifies MDs, parents on diarrhea vaccine
Feb 14, 2007 | Philadelphia Inquirer
The Food and Drug Administration yesterday notified pediatricians and parents of 28 cases of a potentially life-threatening condition in infants and children vaccinated against rotavirus, a leading cause of severe diarrhea worldwide. The agency said the cases of intussusception, in which the intestine becomes twisted and blocked, were not necessarily caused by Merck & Co.'s year-old RotaTeq vaccine. The problem occurs naturally in about one in 2,000 youngsters. The announcement, coming...
Merck Vaccine's Label Revised
Feb 14, 2007 | www.thestreet.com
The Food and Drug Administration is telling consumers and doctors to be aware of a serious potential side effect from a Merck (MRK) vaccine that protects infants against virus-induced diarrhea, vomiting and fever. There haven't been any deaths associated with Merck's RotaTeq vaccine, which guards against the highly contagious rotavirus, the FDA said Tuesday after the markets had closed. However, the agency has received reports of 28 cases of a complication in which an infant's intestine gets...
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Quick Facts
Intussusception Reference Guide
What Is Intussusception?
Intestinal obstruction
Whose at Risk?
Infants
Symptoms
Severe abdominal pain
Blood & mucus in stool
Lump in abdomen
Swollen abdomen
Vomiting
Diarrhea
Fever
Dehydration
Lethargy
Causes
RotaTeq
Related Topics
RotaTeq
Defective Drugs
Diseases
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